A Vankel dissolution tester is a laboratory instrument used in the pharmaceutical industry to assess the rate at which a solid dosage form, such as a tablet or capsule, dissolves under specific conditions. This VK-7000 Vankel dissolution apparatus is a critical step in pharmaceutical quality control and is essential for ensuring the efficacy and bioavailability of a drug.
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Sample Preparation: The pharmaceutical sample, usually a tablet or capsule, is placed in a dissolution test apparatus. The sample is typically inserted into a basket or a paddle, depending on the type of apparatus being used.
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Dissolution Medium: A dissolution medium, which simulates the conditions of the human gastrointestinal tract, is added to the dissolution vessel. This medium is carefully controlled in terms of temperature, pH, and other parameters to mimic the environment in which the drug will be taken.
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Agitation: The dissolution tester agitates the dissolution medium to ensure proper mixing and to simulate the movement of fluids in the human digestive system.
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Sampling: At predetermined time intervals, samples are withdrawn from the dissolution vessel. The concentration of the dissolved drug in each sample is then analyzed to determine the dissolution profile.
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Analysis: The analysis of the samples can be done using various techniques, such as UV-Visible spectroscopy or high-performance liquid chromatography (HPLC), depending on the characteristics of the drug.
Dimensions : L 40 x W 48 x H 43
180LBS
